Validation of AclarusDxTM a blood-based transcriptomic signature for the diagnosis of Alzheimer’s Disease

Manuscript Number: 

12-0637R1

Author(s): 
Thierry Dantoine, Laurent Desire, Richard Einstein, Pascale Fehlbaum-Beurdeley, Audrey Gabelle, Raphael Haddad, Harald Hampel, Anne-Charlotte Jarrige, Jean Christophe Lemarie, Olivier Sol, Jacques Touchon, Bruno Vellas, Martine Vercelletto, Weiyin Zhou

Disclosures

Thierry Dantoine

  • Nothing to Disclose

Laurent Desire

  • Equity:
    Dr Désiré holds stock options from Exonhit
    Sponsors:
    Dr Désiré is employed by Exonhit

Richard Einstein

  • Equity:
    I am an ex-employee of Exonhit, SA, and currently maintain stock options.
    Sponsors:
    ex-employee of the sponsor. Currently work for another commercial entity not associated with Exonhit or Alzheimer's disease
    Patents/Royalties
    I am an ex-employee of Exonhit where one of my responsibilities was patent review.

Pascale Fehlbaum-Beurdeley

  • Equity:
    I hold shares and stock options of Exonhit
    Sponsors:
    I am employee of Exonhit
    Patents/Royalties
    I am author of patents owned by Exonhit

Audrey Gabelle

  • Nothing to Disclose

Raphael Haddad

  • Equity:
    I hold shares of Exonhit
    Sponsors:
    I am employee of Exonhit

Harald Hampel

  • Consulting Fees:
    Eli Lilly, Avid, Sanofi-Aventis, Elan, Astra Zeneca, Schwabe, Boehringer-Ingelheim, GE, Roche, Bayer, BMS, Novartis, Genentech
    Lecture Fees:
    Pfizer, Novartis, Sanofi-Aventis, Merz, Schwabe, Boehringer-Ingelheim
    Patents/Royalties
    patent submissions (pending) as scientific co-inventor, no royalties, no other activities

Anne-Charlotte Jarrige

  • Equity:
    I hold shares of Exonhit
    Sponsors:
    I am employee of Exonhit
    Patents/Royalties
    I am author of patents owned by Exonhit

Jean Christophe Lemarie

  • Consulting Fees:
    I am employed by Effi-Stat, a contract research organisation, contracted by Exonhit (and other companies) for statistical services

Olivier Sol

  • Consulting Fees:
    employee of Exonhit and perceived a salary as a Medical Director of the company.
    Sponsors:
    I was a full-time employee of Exonhit up to the time of submitting the article. I was one of the main writter of the article and also of the protocol of the study. I fully participate in study-related work and data review.

Jacques Touchon

  • Consulting Fees:
    Advisory Board Eisai, Exhonit, Novartis, Lundbeck and IPSEN
    Lecture Fees:
    Speaker fees Eisai, Exhonit, Novartis, Lundbeck and IPSEN

Bruno Vellas

  • Consulting Fees:
    advisory board exhonit 2010
    Grants
    • Agency: 
      exhonit,
      Dates: 
      2009 2010

Martine Vercelletto

  • Nothing to Disclose

Weiyin Zhou

  • Equity:
    stock options
    Patents/Royalties
    patent for "PROCESSES AND METHODS FOR DIAGNOSIS OF ALZHEIMER'S DISEASE"