Small molecule p75NTR ligands reduce pathological phosphorylation and misfolding of tau, inflammatory changes, cholinergic degeneration, and cognitive deficits in AbetaPPL/S transgenic mice

Manuscript Number: 

14-0036R1

Author(s): 
Nadia P. Belichenko, Frank M. Longo, Stephen M. Massa, Thuy-Vi V. Nguyen, Lisa N. Quach, Nay Saw, Mehrdad Shamloo, Lin Shen, Lilith Vander Griend, Tony Wyss-Coray, Tao Yang

Disclosures

Nadia P. Belichenko

  • Nothing to Disclose

Frank M. Longo

  • Consulting Fees:
    Dr. Longo serves as a paid consultant for PharmatrophiX, a company developing small molecule ligands for neurotrophin receptors.
    Equity:
    Dr. Longo holds equity in PharmatrophiX
    Patents/Royalties
    Dr. Longo is an inventor on patents for small molecule neurotrophin receptor ligands and serves as a paid consultant for PharmatrophiX.

Stephen M. Massa

  • Patents/Royalties
    I am listed as an inventor on relevant patents. These patents are owned by UNC, UCSF and the Veterans Administration. I am eligible for royalty distribution from these patents.

Thuy-Vi V. Nguyen

  • Nothing to Disclose

Lisa N. Quach

  • Nothing to Disclose

Nay Saw

  • Nothing to Disclose

Mehrdad Shamloo

  • Nothing to Disclose

Lin Shen

  • Nothing to Disclose

Lilith Vander Griend

  • Nothing to Disclose

Tony Wyss-Coray

  • Nothing to Disclose

Tao Yang

  • Nothing to Disclose