Title | Death Rate Due to COVID-19 in Alzheimer's Disease and Frontotemporal Dementia. |
Publication Type | Journal Article |
Year of Publication | 2020 |
Authors | Matías-Guiu, JA, Pytel, V, Matías-Guiu, J |
Journal | J Alzheimers Dis |
Volume | 78 |
Issue | 2 |
Pagination | 537-541 |
Date Published | 2020 |
ISSN | 1875-8908 |
Keywords | Age Factors, Aged, Aged, 80 and over, Alzheimer Disease, Coronavirus Infections, COVID-19, Female, Frontotemporal Dementia, Humans, Hypertension, Independent Living, Male, Nursing Homes, Pandemics, Pneumonia, Viral, Prevalence, Risk Factors |
Abstract | We aimed to evaluate the frequency and mortality of COVID-19 in patients with Alzheimer's disease (AD) and frontotemporal dementia (FTD). We conducted an observational case series. We enrolled 204 patients, 15.2% of whom were diagnosed with COVID-19, and 41.9% of patients with the infection died. Patients with AD were older than patients with FTD (80.36±8.77 versus 72.00±8.35 years old) and had a higher prevalence of arterial hypertension (55.8% versus 26.3%). COVID-19 occurred in 7.3% of patients living at home, but 72.0% of those living at care homes. Living in care facilities and diagnosis of AD were independently associated with a higher probability of death. We found that living in care homes is the most relevant factor for an increased risk of COVID-19 infection and death, with AD patients exhibiting a higher risk than those with FTD. |
DOI | 10.3233/JAD-200940 |
Alternate Journal | J Alzheimers Dis |
PubMed ID | 33074240 |