Biography & Research:
* Studies on cerebrospinal fluid biochemical markers for clinical diagnosis of AD and therapy monitoring in AD and other brain disorders, including methodological aspects of cerebrospinal fluid analyses and assay development.
* The neurochemical pathogenesis of AD, with focus on APP/Aβ metabolism and aggregation, neuronal and synaptic degeneration, and mechanisms for the APOE ε4 allele.
* Pathogenesis of and diagnostic markers for traumatic brain injury (TBI)