Reduction of RPT6/S8 (a Proteasome component) and proteasome activity in the cortex is associated with cognitive impairment in Lewy body dementia

Manuscript Number: 

16-0946R2

Author(s): 
Dag Aarsland, Amani Alghamdi, Johannes Attems, Clive G. Ballard, Martin Broadstock, Paul T. Francis, Tibor Hortobágyi, David Howlett, John T. O’Brien, Alan J. Thomas, Julie Vallortigara, David Whitfield

Disclosures

Dag Aarsland

  • Consulting Fees:
    Dr Aarsland has received research support and/or honoraria from Astra-Zeneca, H. Lundbeck, Novartis Pharmaceuticals and GE Health, and serves as paid consultant for H. Lundbeck, Eisai, and Axovant. Dag Aarsland is a Royal Society Wolfson Research Merit Award Holder and would like to thank the Wolfson Foundation and the Royal Society for their support
    Lecture Fees:
    Dr Aarsland has received research support and/or honoraria from Astra-Zeneca, H. Lundbeck, Novartis Pharmaceuticals and GE Health, and serves as paid consultant for H. Lundbeck, Eisai, and Axovant.

Amani Alghamdi

  • Nothing to Disclose

Johannes Attems

  • Nothing to Disclose

Clive G. Ballard

  • Consulting Fees:
    personal fees from Roche, Orion, GlaxoSmithKline, Otusaka, Heptares and Lilly. D.A. has received research support and/or honoraria from Astra-Zeneca, H. Lundbeck, Novartis Pharmaceuticals and GE Health, paid consultant for H. Lundbeck and Axovant
    Grants
    • Agency: 
      Lundbeck
      Dates: 
      ongoing
    • Agency: 
      Acadia
      Dates: 
      onging

Martin Broadstock

  • Nothing to Disclose

Paul T. Francis

  • Nothing to Disclose

Tibor Hortobágyi

  • Nothing to Disclose

David Howlett

  • Nothing to Disclose

John T. O’Brien

  • Nothing to Disclose

Alan J. Thomas

  • Nothing to Disclose

Julie Vallortigara

  • Nothing to Disclose

David Whitfield

  • Nothing to Disclose