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6 July 2017

UVA Study Focuses on ‘Speed Bumps’ Protecting Against Alzheimer’s Disease

George Bloom

Dedicated to the study of Alzheimer’s disease, University of Virginia biology professor George Bloom’s lab has spent the last decade working to expand the scientific community’s still-primitive understanding of the disease’s underlying biology. A recently published study from Bloom’s lab is helping to solve one of the devastating brain disorder’s underlying mysteries, explaining how certain proteins convert previously healthy nerve cells into neurons afflicted with Alzheimer’s.

28 June 2017

Anti-Epilepsy Drug Restores Normal Brain Activity in Mild Alzheimer’s disease

Daniel Press, MD

In the last decade, mounting evidence has linked seizure-like activity in the brain to some of the cognitive decline seen in patients with Alzheimer’s disease. Patients with Alzheimer’s disease have an increased risk of epilepsy and nearly half may experience subclinical epileptic activity – disrupted electrical activity in the brain that doesn’t result in a seizure but which can be measured by electroencephalogram (EEG) or other brain scan technology.

27 June 2017

Shi-Jiang Li, PhD, Receives 2017 Alzheimer Award

Shi-Jiang Li, PhD

JAD is pleased to announce that Shi-Jiang Li, PhD, Professor of Biophysics, Radiology, and Psychiatry and Behavioral Medicine at the Medical College of Wisconsin, has been chosen as the recipient of the 2017 Alzheimer Award. It has been presented by the journal in recognition of his outstanding work on the development of the CARE index, potentially a significant new tool in the battle against Alzheimer’s disease (AD) that can be used to characterize risks associated with AD stages and quantify disease severity on an individual subject basis.

8 June 2017

Culprit hidden in plain sight in Alzheimer’s disease development: Combustion-derived nanoparticles in key brain target cells and organelles in young urbanites

A new study by researchers at the University of Montana, Universidad del Valle de México, Instituto Nacional de Pediatría, Boise State, and Universidad Nacional Autónoma de México, heightens concerns over the detrimental short- and long-term impact of airborne iron-rich strongly magnetic combustion-derived nanoparticles (CDNPs) present in young urbanites’ brains. The researchers documented by abundant combustion nanoparticles in neurons, glial cells, choroid plexus, and neurovascular units of Mexico City children, teens and young adults chronically exposed to concentrations above the US-EPA standards for fine particulate matter.

19 May 2017

Can Omega-3 Help Prevent Alzheimer’s Disease? Brain SPECT Imaging Shows Possible Link

The incidence of Alzheimer’s disease (AD) is expected to triple in the coming decades and no cure has been found. Recently, interest in dietary approaches for prevention of cognitive decline has increased. In particular, the omega-3 fatty acids have shown anti-amyloid, anti-tau and anti-inflammatory actions in the brains of animals. In a new article published in the Journal of Alzheimer’s Disease, researchers have found that for patients with high omega-3 levels, blood flow in specific areas of the brain is increased.

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