Neuronal activity regulates the regional vulnerability to amyloid-β deposition.

Bero AW, Yan P, Roh JHoon, Cirrito JR, Stewart FR, Raichle ME, Lee J-M, Holtzman DM
Nat Neurosci. 2011 Jun; 14(6):750-6. PMID: 21532579. Abstract
Top50 Topics: 
Amyloid beta, Pathology


Submitted by YuHong Fu, PhD on

The study suggests a mechanism to account for the vulnerability of specific brain regions to Aβ deposition in Alzheimer's disease.