Larry Schmued, PhD

JAD profile

Associate Editor

Term Expiration: 

12/31/2024

Affiliation(s): 

Histo-Chem Inc.

Areas of Interest: 

Histochemical localization and characterization of AD pathologies in human and murine brain tissue sections, the role of metals and lipids in AD pathologies, the role of metal chelators in the potential treatment of AD.

Biography & Research: 

After receiving a PhD degree from UCI in neuroanatomy, I spent the next decade characterizing neuronal circuitry in the rat brain using anatomical tract tracers we developed. Upon employment with the National Center for Toxicological Research, a branch of the FDA, I began studying the brain pathologies associated with various drugs or food contaminants of FDA interest. Most recently, we have been studying the pathology of the brains of human AD patients as well as mouse models of AD. Although we have studied a variety of potential AD treatments, among the most promising were metal chelators such as cliquinol, deferoxamine, and, most recently, phenanthroline-amine. Biography is available upon request.